Detalhe da pesquisa
1.
Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress.
Mol Cell
; 83(18): 3333-3346.e5, 2023 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738964
2.
KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
Cell
; 161(2): 333-47, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25860612
3.
The unravelling of the ubiquitin system.
Nat Rev Mol Cell Biol
; 16(5): 322-4, 2015 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25907614
4.
The N-Degron Pathway Mediates ER-phagy.
Mol Cell
; 75(5): 1058-1072.e9, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31375263
5.
A short binding site in the KPC1 ubiquitin ligase mediates processing of NF-κB1 p105 to p50: A potential for a tumor-suppressive PROTAC.
Proc Natl Acad Sci U S A
; 118(49)2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34873064
6.
p62-containing, proteolytically active nuclear condensates, increase the efficiency of the ubiquitin-proteasome system.
Proc Natl Acad Sci U S A
; 118(33)2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385323
7.
The N-terminal cysteine is a dual sensor of oxygen and oxidative stress.
Proc Natl Acad Sci U S A
; 118(50)2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34893540
8.
Stress-Induced Proteasome Sub-Cellular Translocation in Cardiomyocytes Causes Altered Intracellular Calcium Handling and Arrhythmias.
Int J Mol Sci
; 25(9)2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38732146
9.
The NF-ĸB p50 subunit generated by KPC1-mediated ubiquitination and limited proteasomal processing, suppresses tumor growth.
Cancer Cell Int
; 23(1): 67, 2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055826
10.
The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation.
Nat Rev Mol Cell Biol
; 12(9): 605-20, 2011 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21860393
11.
Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms.
Proc Natl Acad Sci U S A
; 117(47): 29823-29831, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168738
12.
Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
Proc Natl Acad Sci U S A
; 117(31): 18661-18669, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32675242
13.
Ubiquitin Proteasome System Role in Diabetes-Induced Cardiomyopathy.
Int J Mol Sci
; 24(20)2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37895057
14.
Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles.
Proc Natl Acad Sci U S A
; 116(16): 7805-7812, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867293
15.
The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy.
Trends Biochem Sci
; 42(11): 873-886, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947091
16.
The p105 NF-ĸB precursor is a pseudo substrate of the ubiquitin ligase FBXO7, and its binding to the ligase stabilizes it and results in stimulated cell proliferation.
Biochem Biophys Res Commun
; 558: 224-230, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32933748
17.
Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Mol Cell
; 50(4): 528-39, 2013 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665229
18.
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Proc Natl Acad Sci U S A
; 115(12): E2716-E2724, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29507222
19.
Moral clarity at WHO needs to be clearer.
Lancet
; 403(10430): 905, 2024 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38373434
20.
Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-Linked Diubiquitin by a Twofold Strategy.
Chemistry
; 26(36): 8022-8027, 2020 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105365